Panhypopituitarism

•↓Adrenal •Hypothyroidism •HypoG •↓GH •DI

CAUSES 
          •Pituitary tumours (incl metastases)
          •Craniopharyngiomas
          •Empty sella syndrome
          •Infiltration (TB, Sarcoidosis, Histiocytosis X)
          •Encephalitis
          •Syphilis
          •Trauma
          •Sheehan's (Pituitary infarction with postpartum haemorrhage)

MANAGEMENT
         •Replace all deficient hormones

Further Reading