Fig 1: Prolactin Structure |
•-ve Hypothalamus control
•↑Dopamine→↓Prolactin
HYPOPROLACTINAEMIA
Causes •Dopamine
•Dopamine agonists (Bromocriptine)
HYPERPROLACTINAEMIA
Symptoms •Galactorrhoea
•Secondary hypogonadism
Causes •Prolactinoma
•Stress (Epileptic fit)
•Pregnancy
•Polycystic ovary
•Damage to hypothalamus/pituitary stalk
•Renal/hepatic failure
•Dopamine antagonist (Metoclopramide, Phenothiazines)
•Oestrogens (OCP)
MNEMONICS Please Buy Raspberries Or Melons To Calm Ellen
Phenothiazines Butyrophenones Reserpine Opiates
Metoclopramide TriCylic Estrogens
Further Reading | Fig 1
No comments:
Post a Comment