Fibrinolytic / Thrombolytic Agents in Acute Myocardial Infarction

The thrombolytic agents approved for use in the UK by the National Institute of Clinical Excellence (NICE) are streptokinase, reteplase, tenecteplase and alteplase.

ASSENT-2 trial

One-year follow-up of the ASSENT-2 trial: a double-blind, randomized comparison of single-bolus tenecteplase and front-loaded alteplase in 16,949 patients with ST-elevation acute myocardial infarction.

Sinnaeve P, Alexander J, Belmans A, Bogaerts K, Langer A, Diaz R, Ardissino D, Vahanian A, Pehrsson K, Armstrong P, Van de Werf F; ASSENT-2 Investigators.
Source

Department of Cardiology, University of Leuven, Leuven, Belgium.