Fibrinolytic / Thrombolytic Agents in Acute Myocardial Infarction

The thrombolytic agents approved for use in the UK by the National Institute of Clinical Excellence (NICE) are streptokinase, reteplase, tenecteplase and alteplase.

GUSTO-I Trial

GUSTO-I

Global Utilization of Streptokinase and t-PA for Occluded coronary arteries – I
   
Author(s)   

• The GUSTO investigators
• Califf RM, White HD, Van de Werf F, Sadowski Z, Armstrong PW, Vahanian A, Simoons ML, Simes RJ, Lee KL, Topol EJ
• White HD, Barbash GI, Califf RM, Simes RJ, Granger CB, Weaver WD, Kleiman NS, Aylward PE, Gore JM, Vahanian A, Lee KL, Ross AM, Topol EJ
• Lesnefsky EJ, Lundergan CF, Hodgson JMcB, Nair R, Reiner JS, Greenhouse SW, Califf RM, Ross AM