Sarcomere disruption in hypertrophic cardiomyopathy (HCM)

Sarcomere disruption in hypertrophic cardiomyopathy (HCM).
ACE = angiotensin-converting enzyme.
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Hypertrophic cardiomyopathy (HCM) is thought to occur primarily through sarcomere disruption in the face of intact cytoskeleton/sarcolemma.