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Showing posts with label autosomal dominant. Show all posts
Showing posts with label autosomal dominant. Show all posts

Risk factors for sudden death in hypertrophic cardiomyopathy (HCM)

Hypetrophic Cardiomyopathy [Source]
Hypertrophic cardiomyopathy (HCM) is the commonest form of cardiomyopathy, with a prevalence 100 per 100,000.

Genetic
It is a genetic disorder with autosomal-dominant transmission, a high degree of penetrance and variable expression.

Clinical features
Symptoms and signs are similar to those of aortic stenosis, except that the character of the pulse is jerky in HCM.