 |
| Fig 1: Diagnosis Cushing's Syndrome ACTH: AdrenoCorticoTropic Hormone; IPSS: Inferior Petrosal Sinus Sampling; CRH: Corticotrophin Releasing Hormone |
↓DOSE: 1-2mg → ↓Cortisol → ΘEndogenous pathology
↑DOSE: 8mg → -Feedback on pituitary
→ ΘFeedback on → Ectopic ACTH
→ Adrenal Adenoma
↓DOSE → ↓Cortisol → Normal -feedback
→ =Cortisol → ↑DOSE → ↓Cortisol → 1ºAdrenal
→ =Cortisol → Ectopic ACTH → CXR/ CT Abdo
→ ↑Cortisol → Cushing's dis → MRI Pituitary, ΘCushingoid
Relevant articles
