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Showing posts with label Analgesic Nephropathy. Show all posts
Showing posts with label Analgesic Nephropathy. Show all posts

Tubulointerstitial Nephritis

+ is primary injury to renal tubules & interstitium resulting in decreased renal function.
+ Etiology
+ + can be primary
+ + + Acute
+ + + Chronic
+ can result from glomerular damage / renovascular disorders 
+ acute form caused by
+ + allergic drug reactions
+ + infections
+ chronic form caused by
+ + genetic / metabolic disorders
+ + obstructive uropathy
+ + chronic exposure to environmental toxins / to certain drugs & herbs
+ Diagnosis
+ + suggested by history & urinalysis
+ + confirmed by biopsy
+ Treatment & prognosis vary by the etiology & potential reversibility of the disorder at the time of diagnosis