American Heart Association 2010 ACLS Algorithm. |
CPR Quality
- Push hard (≥2 inches [5 cm]) and fast (≥100/min) and allow complete chest recoil
- Minimize interruptions in compressions
- Avoid excessive ventilation
- Rotate compressor every 2 minutes
- If no advanced airway, 30:2 compression-ventilation ratio
- Quantitative waveform capnography
- If Petco2 <10 mm Hg, attempt to improve CPR quality
- Intra-arterial pressure
- If relaxation phase (diastolic) pressure <20 mm Hg, attempt to improve CPR quality
Return of Spontaneous Circulation (ROSC)
- Pulse and blood pressure
- Abrupt sustained increase in Petco2 (typically ≥40 mm Hg)
- Spontaneous arterial pressure waves with intra-arterial monitoring
Shock Energy
- Biphasic: Manufacturer recommendation (120-200 J); if unknown, use maximum available. Second and subsequent doses should be equivalent, and higher doses may be considered.
- Monophasic: 360 J
Drug Therapy
- Epinephrine IV/IO Dose: 1 mg every 3-5 minutes
- Vasopressin IV/IO Dose: 40 units can replace first or second dose of epinephrine
- Amiodarone IV/IO Dose: First dose: 300 mg bolus. Second dose: 150 mg.
Advanced Airway
- Supraglottic advanced airway or endotracheal intubation
- Waveform capnography to confirm and monitor ET tube placement
- 8-10 breaths per minute with continuous chest compressions
Reversible Causes
- Hypovolemia
- Hypoxia
- Hydrogen ion (acidosis)
- Hypo-/hyperkalemia
- Hypothermia
- Tension pneumothorax
- Tamponade, cardiac
- Toxins
- Thrombosis, pulmonary
- Thrombosis, coronary
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