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AHA 2010 ACLS Algorithm


American Heart Association 2010 ACLS Algorithm.

CPR Quality

  • Push hard (≥2 inches [5 cm]) and fast (≥100/min) and allow complete chest recoil
  • Minimize interruptions in compressions
  • Avoid excessive ventilation
  • Rotate compressor every 2 minutes
  • If no advanced airway, 30:2 compression-ventilation ratio
  • Quantitative waveform capnography
    • If Petco2 <10 mm Hg, attempt to improve CPR quality
  • Intra-arterial pressure
    • If relaxation phase (diastolic) pressure <20 mm Hg, attempt to improve CPR quality

Return of Spontaneous Circulation (ROSC)
  • Pulse and blood pressure
  • Abrupt sustained increase in Petco2 (typically ≥40 mm Hg)
  • Spontaneous arterial pressure waves with intra-arterial monitoring

Shock Energy
  • Biphasic: Manufacturer recommendation (120-200 J); if unknown, use maximum available. Second and subsequent doses should be equivalent, and higher doses may be considered.
  • Monophasic: 360 J

Drug Therapy
  • Epinephrine IV/IO Dose: 1 mg every 3-5 minutes
  • Vasopressin IV/IO Dose: 40 units can replace first or second dose of epinephrine
  • Amiodarone IV/IO Dose: First dose: 300 mg bolus. Second dose: 150 mg.

Advanced Airway
  • Supraglottic advanced airway or endotracheal intubation
  • Waveform capnography to confirm and monitor ET tube placement
  • 8-10 breaths per minute with continuous chest compressions

Reversible Causes
  • Hypovolemia
  • Hypoxia
  • Hydrogen ion (acidosis)
  • Hypo-/hyperkalemia
  • Hypothermia
  • Tension pneumothorax
  • Tamponade, cardiac
  • Toxins
  • Thrombosis, pulmonary
  • Thrombosis, coronary



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