cup-shaped pneumocystis carinii |
CXR signs in PCP |
Pneumocystis jiroveci pneumonia is treated with high percentage oxygen and the drug of choice is high dose IV cotrimoxazole (trimethoprim-sulphamethoxazole). If allergic to co-trimoxazole, IV pentamidine or Clindamycin are appropriate. IV leucovirin and oral atovaquone are further options but are not first line therapies. Prednisolone has been shown to reduce mortality substantially in patients with a PO2< 60mmHg.
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